Serveur d'exploration sur la COVID chez les séniors

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Acute stroke care in a New York City comprehensive stroke center during the COVID-19 pandemic.

Identifieur interne : 000957 ( Main/Exploration ); précédent : 000956; suivant : 000958

Acute stroke care in a New York City comprehensive stroke center during the COVID-19 pandemic.

Auteurs : Shashank Agarwal [États-Unis] ; Erica Scher [États-Unis] ; Nirmala Rossan-Raghunath [États-Unis] ; Dilshad Marolia [États-Unis] ; Mariya Butnar [États-Unis] ; Jose Torres [États-Unis] ; Cen Zhang [États-Unis] ; Sun Kim [États-Unis] ; Matthew Sanger [États-Unis] ; Kelley Humbert [États-Unis] ; Omar Tanweer [États-Unis] ; Maksim Shapiro [États-Unis] ; Eytan Raz [États-Unis] ; Erez Nossek [États-Unis] ; Peter K. Nelson [États-Unis] ; Howard A. Riina [États-Unis] ; Adam De Havenon [États-Unis] ; Michael Wachs [États-Unis] ; Jeffrey Farkas [États-Unis] ; Ambooj Tiwari [États-Unis] ; Karthikeyan Arcot [États-Unis] ; David Turkel Parella [États-Unis] ; Jeremy Liff [États-Unis] ; Tina Wu [États-Unis] ; Ian Wittman [États-Unis] ; Reed Caldwell [États-Unis] ; Jennifer Frontera [États-Unis] ; Aaron Lord [États-Unis] ; Koto Ishida [États-Unis] ; Shadi Yaghi [États-Unis]

Source :

RBID : pubmed:32807471

Descripteurs français

English descriptors

Abstract

BACKGROUND AND PURPOSE

The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented demand and burden on emergency health care services in New York City. We aim to describe our experience providing acute stroke care at a comprehensive stroke center (CSC) and the impact of the pandemic on the quality of care for patients presenting with acute ischemic stroke (AIS).

METHODS

We retrospectively analyzed data from a quality improvement registry of consecutive AIS patients at New York University Langone Health's CSC between 06/01/2019-05/15/2020. During the early stages of the pandemic, the acute stroke process was modified to incorporate COVID-19 screening, testing, and other precautionary measures. We compared stroke quality metrics including treatment times and discharge outcomes of AIS patients during the pandemic (03/012020-05/152020) compared with a historical pre-pandemic group (6/1/2019-2/29/2020).

RESULTS

A total of 754 patients (pandemic-120; pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%) received alteplase and/or mechanical thrombectomy. Despite longer median door to head CT times (16 vs 12 minutes; p = 0.05) and a trend towards longer door to groin puncture times (79.5 vs. 71 min, p = 0.06), the time to alteplase administration (36 vs 35 min; p = 0.83), door to reperfusion times (103 vs 97 min, p = 0.18) and defect-free care (95.2% vs 94.7%; p = 0.84) were similar in the pandemic and pre-pandemic groups. Successful recanalization rates (TICI≥2b) were also similar (82.6% vs. 86.7%, p = 0.48). After adjusting for stroke severity, age and a prior history of transient ischemic attack/stroke, pandemic patients had increased discharge mortality (adjusted OR 2.90 95% CI 1.77 - 7.17, p = 0.021) CONCLUSION: Despite unprecedented demands on emergency healthcare services, early multidisciplinary efforts to adapt the acute stroke treatment process resulted in keeping the stroke quality time metrics close to pre-pandemic levels. Future studies will be needed with a larger cohort comparing discharge and long-term outcomes between pre-pandemic and pandemic AIS patients.


DOI: 10.1016/j.jstrokecerebrovasdis.2020.105068
PubMed: 32807471
PubMed Central: PMC7305900


Affiliations:


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<name sortKey="Wu, Tina" sort="Wu, Tina" uniqKey="Wu T" first="Tina" last="Wu">Tina Wu</name>
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<name sortKey="Rossan Raghunath, Nirmala" sort="Rossan Raghunath, Nirmala" uniqKey="Rossan Raghunath N" first="Nirmala" last="Rossan-Raghunath">Nirmala Rossan-Raghunath</name>
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<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Nirmala.Rossan-Raghunath@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Marolia, Dilshad" sort="Marolia, Dilshad" uniqKey="Marolia D" first="Dilshad" last="Marolia">Dilshad Marolia</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Dilshad.Marolia@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Butnar, Mariya" sort="Butnar, Mariya" uniqKey="Butnar M" first="Mariya" last="Butnar">Mariya Butnar</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Mariya.Butnar@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Torres, Jose" sort="Torres, Jose" uniqKey="Torres J" first="Jose" last="Torres">Jose Torres</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jose.Torres2@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Zhang, Cen" sort="Zhang, Cen" uniqKey="Zhang C" first="Cen" last="Zhang">Cen Zhang</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Cen.Zhang@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kim, Sun" sort="Kim, Sun" uniqKey="Kim S" first="Sun" last="Kim">Sun Kim</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Sun.Kim@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sanger, Matthew" sort="Sanger, Matthew" uniqKey="Sanger M" first="Matthew" last="Sanger">Matthew Sanger</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Matt.Sanger@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Humbert, Kelley" sort="Humbert, Kelley" uniqKey="Humbert K" first="Kelley" last="Humbert">Kelley Humbert</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Kelley.Humbert@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tanweer, Omar" sort="Tanweer, Omar" uniqKey="Tanweer O" first="Omar" last="Tanweer">Omar Tanweer</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Omar.Tanweer@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Shapiro, Maksim" sort="Shapiro, Maksim" uniqKey="Shapiro M" first="Maksim" last="Shapiro">Maksim Shapiro</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Maksim.Shapiro@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Raz, Eytan" sort="Raz, Eytan" uniqKey="Raz E" first="Eytan" last="Raz">Eytan Raz</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Eytan.Raz@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nossek, Erez" sort="Nossek, Erez" uniqKey="Nossek E" first="Erez" last="Nossek">Erez Nossek</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Erez.Nossek@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Nelson, Peter K" sort="Nelson, Peter K" uniqKey="Nelson P" first="Peter K" last="Nelson">Peter K. Nelson</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Peter.Nelson@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Riina, Howard A" sort="Riina, Howard A" uniqKey="Riina H" first="Howard A" last="Riina">Howard A. Riina</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Howard.Riina@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="De Havenon, Adam" sort="De Havenon, Adam" uniqKey="De Havenon A" first="Adam" last="De Havenon">Adam De Havenon</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, University of Utah, Salt Lake City, UT, United States. Electronic address: Adam.DeHavenon@hsc.utah.edu.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Utah, Salt Lake City, UT</wicri:regionArea>
<placeName>
<region type="state">Utah</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wachs, Michael" sort="Wachs, Michael" uniqKey="Wachs M" first="Michael" last="Wachs">Michael Wachs</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Michael.Wachs@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Farkas, Jeffrey" sort="Farkas, Jeffrey" uniqKey="Farkas J" first="Jeffrey" last="Farkas">Jeffrey Farkas</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jeffrey.Farkas@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Tiwari, Ambooj" sort="Tiwari, Ambooj" uniqKey="Tiwari A" first="Ambooj" last="Tiwari">Ambooj Tiwari</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Ambooj.Tiwari@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Arcot, Karthikeyan" sort="Arcot, Karthikeyan" uniqKey="Arcot K" first="Karthikeyan" last="Arcot">Karthikeyan Arcot</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Karthikeyan.Arcot@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Parella, David Turkel" sort="Parella, David Turkel" uniqKey="Parella D" first="David Turkel" last="Parella">David Turkel Parella</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: David.Turkel-Parrella@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Liff, Jeremy" sort="Liff, Jeremy" uniqKey="Liff J" first="Jeremy" last="Liff">Jeremy Liff</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jeremy.Liff@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wu, Tina" sort="Wu, Tina" uniqKey="Wu T" first="Tina" last="Wu">Tina Wu</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Tina.Wu@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Emergency Medicine, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wittman, Ian" sort="Wittman, Ian" uniqKey="Wittman I" first="Ian" last="Wittman">Ian Wittman</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Ian.Wittman@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Emergency Medicine, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Caldwell, Reed" sort="Caldwell, Reed" uniqKey="Caldwell R" first="Reed" last="Caldwell">Reed Caldwell</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Reed.Caldwell@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Emergency Medicine, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Frontera, Jennifer" sort="Frontera, Jennifer" uniqKey="Frontera J" first="Jennifer" last="Frontera">Jennifer Frontera</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jennifer.Frontera@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Lord, Aaron" sort="Lord, Aaron" uniqKey="Lord A" first="Aaron" last="Lord">Aaron Lord</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Aaron.Lord@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ishida, Koto" sort="Ishida, Koto" uniqKey="Ishida K" first="Koto" last="Ishida">Koto Ishida</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Koto.Ishida@nyulangone.org.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Yaghi, Shadi" sort="Yaghi, Shadi" uniqKey="Yaghi S" first="Shadi" last="Yaghi">Shadi Yaghi</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: shadiyaghi@yahoo.com.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, New York Langone Health, New York, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association</title>
<idno type="eISSN">1532-8511</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>Comprehensive Health Care (organization & administration)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Coronavirus Infections (virology)</term>
<term>Critical Pathways (organization & administration)</term>
<term>Delivery of Health Care, Integrated (organization & administration)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>New York City (epidemiology)</term>
<term>Pandemics (MeSH)</term>
<term>Patient Care Team (organization & administration)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (therapy)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Quality Improvement (organization & administration)</term>
<term>Quality Indicators, Health Care (organization & administration)</term>
<term>Registries (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Stroke (diagnosis)</term>
<term>Stroke (epidemiology)</term>
<term>Stroke (therapy)</term>
<term>Thrombectomy (MeSH)</term>
<term>Thrombolytic Therapy (MeSH)</term>
<term>Time Factors (MeSH)</term>
<term>Time-to-Treatment (organization & administration)</term>
<term>Treatment Outcome (MeSH)</term>
<term>Workflow (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Accident vasculaire cérébral (diagnostic)</term>
<term>Accident vasculaire cérébral (thérapie)</term>
<term>Accident vasculaire cérébral (épidémiologie)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Amélioration de la qualité (organisation et administration)</term>
<term>Betacoronavirus (pathogénicité)</term>
<term>Délai jusqu'au traitement (organisation et administration)</term>
<term>Enregistrements (MeSH)</term>
<term>Facteurs temps (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Flux de travaux (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Indicateurs qualité santé (organisation et administration)</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (thérapie)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Mâle (MeSH)</term>
<term>New York (ville) (épidémiologie)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (thérapie)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Prestation intégrée de soins de santé (organisation et administration)</term>
<term>Programme clinique (organisation et administration)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Services de santé polyvalents (organisation et administration)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Thrombectomie (MeSH)</term>
<term>Traitement thrombolytique (MeSH)</term>
<term>Équipe soignante (organisation et administration)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en">
<term>New York City</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="organisation et administration" xml:lang="fr">
<term>Amélioration de la qualité</term>
<term>Délai jusqu'au traitement</term>
<term>Indicateurs qualité santé</term>
<term>Prestation intégrée de soins de santé</term>
<term>Programme clinique</term>
<term>Services de santé polyvalents</term>
<term>Équipe soignante</term>
</keywords>
<keywords scheme="MESH" qualifier="organization & administration" xml:lang="en">
<term>Comprehensive Health Care</term>
<term>Critical Pathways</term>
<term>Delivery of Health Care, Integrated</term>
<term>Patient Care Team</term>
<term>Quality Improvement</term>
<term>Quality Indicators, Health Care</term>
<term>Time-to-Treatment</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en">
<term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr">
<term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr">
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Infections à coronavirus</term>
<term>New York (ville)</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Registries</term>
<term>Retrospective Studies</term>
<term>Thrombectomy</term>
<term>Thrombolytic Therapy</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Workflow</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Enregistrements</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Flux de travaux</term>
<term>Humains</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thrombectomie</term>
<term>Traitement thrombolytique</term>
<term>Études rétrospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<b>BACKGROUND AND PURPOSE</b>
</p>
<p>The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented demand and burden on emergency health care services in New York City. We aim to describe our experience providing acute stroke care at a comprehensive stroke center (CSC) and the impact of the pandemic on the quality of care for patients presenting with acute ischemic stroke (AIS).</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>We retrospectively analyzed data from a quality improvement registry of consecutive AIS patients at New York University Langone Health's CSC between 06/01/2019-05/15/2020. During the early stages of the pandemic, the acute stroke process was modified to incorporate COVID-19 screening, testing, and other precautionary measures. We compared stroke quality metrics including treatment times and discharge outcomes of AIS patients during the pandemic (03/012020-05/152020) compared with a historical pre-pandemic group (6/1/2019-2/29/2020).</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A total of 754 patients (pandemic-120; pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%) received alteplase and/or mechanical thrombectomy. Despite longer median door to head CT times (16 vs 12 minutes; p = 0.05) and a trend towards longer door to groin puncture times (79.5 vs. 71 min, p = 0.06), the time to alteplase administration (36 vs 35 min; p = 0.83), door to reperfusion times (103 vs 97 min, p = 0.18) and defect-free care (95.2% vs 94.7%; p = 0.84) were similar in the pandemic and pre-pandemic groups. Successful recanalization rates (TICI≥2b) were also similar (82.6% vs. 86.7%, p = 0.48). After adjusting for stroke severity, age and a prior history of transient ischemic attack/stroke, pandemic patients had increased discharge mortality (adjusted OR 2.90 95% CI 1.77 - 7.17, p = 0.021) CONCLUSION: Despite unprecedented demands on emergency healthcare services, early multidisciplinary efforts to adapt the acute stroke treatment process resulted in keeping the stroke quality time metrics close to pre-pandemic levels. Future studies will be needed with a larger cohort comparing discharge and long-term outcomes between pre-pandemic and pandemic AIS patients.</p>
</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">32807471</PMID>
<DateCompleted>
<Year>2020</Year>
<Month>08</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised>
<Year>2020</Year>
<Month>10</Month>
<Day>03</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1532-8511</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>29</Volume>
<Issue>9</Issue>
<PubDate>
<Year>2020</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association</Title>
<ISOAbbreviation>J Stroke Cerebrovasc Dis</ISOAbbreviation>
</Journal>
<ArticleTitle>Acute stroke care in a New York City comprehensive stroke center during the COVID-19 pandemic.</ArticleTitle>
<Pagination>
<MedlinePgn>105068</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S1052-3057(20)30486-9</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jstrokecerebrovasdis.2020.105068</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND AND PURPOSE" NlmCategory="OBJECTIVE">The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented demand and burden on emergency health care services in New York City. We aim to describe our experience providing acute stroke care at a comprehensive stroke center (CSC) and the impact of the pandemic on the quality of care for patients presenting with acute ischemic stroke (AIS).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We retrospectively analyzed data from a quality improvement registry of consecutive AIS patients at New York University Langone Health's CSC between 06/01/2019-05/15/2020. During the early stages of the pandemic, the acute stroke process was modified to incorporate COVID-19 screening, testing, and other precautionary measures. We compared stroke quality metrics including treatment times and discharge outcomes of AIS patients during the pandemic (03/012020-05/152020) compared with a historical pre-pandemic group (6/1/2019-2/29/2020).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 754 patients (pandemic-120; pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%) received alteplase and/or mechanical thrombectomy. Despite longer median door to head CT times (16 vs 12 minutes; p = 0.05) and a trend towards longer door to groin puncture times (79.5 vs. 71 min, p = 0.06), the time to alteplase administration (36 vs 35 min; p = 0.83), door to reperfusion times (103 vs 97 min, p = 0.18) and defect-free care (95.2% vs 94.7%; p = 0.84) were similar in the pandemic and pre-pandemic groups. Successful recanalization rates (TICI≥2b) were also similar (82.6% vs. 86.7%, p = 0.48). After adjusting for stroke severity, age and a prior history of transient ischemic attack/stroke, pandemic patients had increased discharge mortality (adjusted OR 2.90 95% CI 1.77 - 7.17, p = 0.021) CONCLUSION: Despite unprecedented demands on emergency healthcare services, early multidisciplinary efforts to adapt the acute stroke treatment process resulted in keeping the stroke quality time metrics close to pre-pandemic levels. Future studies will be needed with a larger cohort comparing discharge and long-term outcomes between pre-pandemic and pandemic AIS patients.</AbstractText>
<CopyrightInformation>Copyright © 2020 Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Agarwal</LastName>
<ForeName>Shashank</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: shashank.agarwal@nyumc.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Scher</LastName>
<ForeName>Erica</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: erica.Scher@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Rossan-Raghunath</LastName>
<ForeName>Nirmala</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Nirmala.Rossan-Raghunath@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Marolia</LastName>
<ForeName>Dilshad</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Dilshad.Marolia@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Butnar</LastName>
<ForeName>Mariya</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Mariya.Butnar@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Torres</LastName>
<ForeName>Jose</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jose.Torres2@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zhang</LastName>
<ForeName>Cen</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Cen.Zhang@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kim</LastName>
<ForeName>Sun</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Sun.Kim@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sanger</LastName>
<ForeName>Matthew</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Matt.Sanger@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Humbert</LastName>
<ForeName>Kelley</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Kelley.Humbert@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tanweer</LastName>
<ForeName>Omar</ForeName>
<Initials>O</Initials>
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<Affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Omar.Tanweer@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Shapiro</LastName>
<ForeName>Maksim</ForeName>
<Initials>M</Initials>
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<Affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Maksim.Shapiro@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Raz</LastName>
<ForeName>Eytan</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Eytan.Raz@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nossek</LastName>
<ForeName>Erez</ForeName>
<Initials>E</Initials>
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<Affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Erez.Nossek@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nelson</LastName>
<ForeName>Peter K</ForeName>
<Initials>PK</Initials>
<AffiliationInfo>
<Affiliation>Department of Radiology, New York Langone Health, New York, NY, United States. Electronic address: Peter.Nelson@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Riina</LastName>
<ForeName>Howard A</ForeName>
<Initials>HA</Initials>
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<Affiliation>Department of Neurosurgery, New York Langone Health, New York, NY, United States. Electronic address: Howard.Riina@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>de Havenon</LastName>
<ForeName>Adam</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, University of Utah, Salt Lake City, UT, United States. Electronic address: Adam.DeHavenon@hsc.utah.edu.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wachs</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Michael.Wachs@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Farkas</LastName>
<ForeName>Jeffrey</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jeffrey.Farkas@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Tiwari</LastName>
<ForeName>Ambooj</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Ambooj.Tiwari@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Arcot</LastName>
<ForeName>Karthikeyan</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Karthikeyan.Arcot@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Parella</LastName>
<ForeName>David Turkel</ForeName>
<Initials>DT</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: David.Turkel-Parrella@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Liff</LastName>
<ForeName>Jeremy</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jeremy.Liff@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wu</LastName>
<ForeName>Tina</ForeName>
<Initials>T</Initials>
<AffiliationInfo>
<Affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Tina.Wu@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wittman</LastName>
<ForeName>Ian</ForeName>
<Initials>I</Initials>
<AffiliationInfo>
<Affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Ian.Wittman@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Caldwell</LastName>
<ForeName>Reed</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Emergency Medicine, New York Langone Health, New York, NY, United States. Electronic address: Reed.Caldwell@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Frontera</LastName>
<ForeName>Jennifer</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Jennifer.Frontera@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Lord</LastName>
<ForeName>Aaron</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Aaron.Lord@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ishida</LastName>
<ForeName>Koto</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: Koto.Ishida@nyulangone.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Yaghi</LastName>
<ForeName>Shadi</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology, New York Langone Health, New York, NY, United States. Electronic address: shadiyaghi@yahoo.com.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2020</Year>
<Month>06</Month>
<Day>20</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo>
<Country>United States</Country>
<MedlineTA>J Stroke Cerebrovasc Dis</MedlineTA>
<NlmUniqueID>9111633</NlmUniqueID>
<ISSNLinking>1052-3057</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList>
<SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D003191" MajorTopicYN="N">Comprehensive Health Care</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="Y">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D019091" MajorTopicYN="N">Critical Pathways</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="N">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D019033" MajorTopicYN="N">Delivery of Health Care, Integrated</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="Y">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D009519" MajorTopicYN="N" Type="Geographic">New York City</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D010348" MajorTopicYN="N">Patient Care Team</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="N">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D058996" MajorTopicYN="N">Quality Improvement</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="Y">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D019984" MajorTopicYN="N">Quality Indicators, Health Care</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="Y">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012042" MajorTopicYN="N">Registries</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D020521" MajorTopicYN="N">Stroke</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017131" MajorTopicYN="Y">Thrombectomy</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015912" MajorTopicYN="Y">Thrombolytic Therapy</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D061665" MajorTopicYN="N">Time-to-Treatment</DescriptorName>
<QualifierName UI="Q000458" MajorTopicYN="N">organization & administration</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D057188" MajorTopicYN="N">Workflow</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">Comprehensive stroke center</Keyword>
<Keyword MajorTopicYN="N">Quality research</Keyword>
<Keyword MajorTopicYN="N">Stroke</Keyword>
</KeywordList>
<CoiStatement>Declaration of Competing Interest None.</CoiStatement>
</MedlineCitation>
<PubmedData>
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<Year>2020</Year>
<Month>05</Month>
<Day>29</Day>
</PubMedPubDate>
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<Year>2020</Year>
<Month>06</Month>
<Day>10</Day>
</PubMedPubDate>
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<Month>06</Month>
<Day>15</Day>
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<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Utah</li>
<li>État de New York</li>
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<name sortKey="Liff, Jeremy" sort="Liff, Jeremy" uniqKey="Liff J" first="Jeremy" last="Liff">Jeremy Liff</name>
<name sortKey="Lord, Aaron" sort="Lord, Aaron" uniqKey="Lord A" first="Aaron" last="Lord">Aaron Lord</name>
<name sortKey="Marolia, Dilshad" sort="Marolia, Dilshad" uniqKey="Marolia D" first="Dilshad" last="Marolia">Dilshad Marolia</name>
<name sortKey="Nelson, Peter K" sort="Nelson, Peter K" uniqKey="Nelson P" first="Peter K" last="Nelson">Peter K. Nelson</name>
<name sortKey="Nossek, Erez" sort="Nossek, Erez" uniqKey="Nossek E" first="Erez" last="Nossek">Erez Nossek</name>
<name sortKey="Parella, David Turkel" sort="Parella, David Turkel" uniqKey="Parella D" first="David Turkel" last="Parella">David Turkel Parella</name>
<name sortKey="Raz, Eytan" sort="Raz, Eytan" uniqKey="Raz E" first="Eytan" last="Raz">Eytan Raz</name>
<name sortKey="Riina, Howard A" sort="Riina, Howard A" uniqKey="Riina H" first="Howard A" last="Riina">Howard A. Riina</name>
<name sortKey="Rossan Raghunath, Nirmala" sort="Rossan Raghunath, Nirmala" uniqKey="Rossan Raghunath N" first="Nirmala" last="Rossan-Raghunath">Nirmala Rossan-Raghunath</name>
<name sortKey="Sanger, Matthew" sort="Sanger, Matthew" uniqKey="Sanger M" first="Matthew" last="Sanger">Matthew Sanger</name>
<name sortKey="Scher, Erica" sort="Scher, Erica" uniqKey="Scher E" first="Erica" last="Scher">Erica Scher</name>
<name sortKey="Shapiro, Maksim" sort="Shapiro, Maksim" uniqKey="Shapiro M" first="Maksim" last="Shapiro">Maksim Shapiro</name>
<name sortKey="Tanweer, Omar" sort="Tanweer, Omar" uniqKey="Tanweer O" first="Omar" last="Tanweer">Omar Tanweer</name>
<name sortKey="Tiwari, Ambooj" sort="Tiwari, Ambooj" uniqKey="Tiwari A" first="Ambooj" last="Tiwari">Ambooj Tiwari</name>
<name sortKey="Torres, Jose" sort="Torres, Jose" uniqKey="Torres J" first="Jose" last="Torres">Jose Torres</name>
<name sortKey="Wachs, Michael" sort="Wachs, Michael" uniqKey="Wachs M" first="Michael" last="Wachs">Michael Wachs</name>
<name sortKey="Wittman, Ian" sort="Wittman, Ian" uniqKey="Wittman I" first="Ian" last="Wittman">Ian Wittman</name>
<name sortKey="Wu, Tina" sort="Wu, Tina" uniqKey="Wu T" first="Tina" last="Wu">Tina Wu</name>
<name sortKey="Yaghi, Shadi" sort="Yaghi, Shadi" uniqKey="Yaghi S" first="Shadi" last="Yaghi">Shadi Yaghi</name>
<name sortKey="Zhang, Cen" sort="Zhang, Cen" uniqKey="Zhang C" first="Cen" last="Zhang">Cen Zhang</name>
</country>
</tree>
</affiliations>
</record>

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